Generally speaking: No. Of course, you decide which wrinkles you want to have treated. Some wrinkles are caused by volume loss of the skin, e.g. the nasolabial folds. Volume loss is compensated with the volume replacement material hyaluron. Likewise, lips can only increase in size by adding volume, i.e. hyaluron filler. Botulinum would only cause severe movement disorders in the lips. Conversely, frown and laugh lines are caused by overactive muscles. Only botulinum intervenes in the muscle activity. In addition, deep frown, forehead and laugh lines can be treated with a thin liquid filler. At the express wish of the patient, treatment with filler alone is also possible, but not optimal.