An injection with filler can trigger a new episode of herpes labialis. If these episodes are very pronounced, prophylactic treatment with aciclovir 2x400mg may be advisable. Alternatively, a treatment with Zovirax cream can be kept ready after the injection, or oral therapy with aciclovir 5x200mg can be started immediately at the first signs of an outbreak.
Botulinum injections in other facial regions do not trigger a herpes spurt.